Imagine sifting through trillions of possibilities, each a potential cure waiting to be discovered. That’s the exhilarating reality of DNA-Encoded Libraries (DELs), a technology revolutionizing drug discovery. But with this boundless power comes a massive challenge – deciphering big data generated by DEL experiments.
That’s where Excelra steps in. We’re data navigators, empowering researchers to conquer the DEL data deluge and unlock the full potential of this groundbreaking technology.
Think of them as treasure troves brimming with billions of tiny molecules, each labeled with a unique DNA barcode. Researchers can screen these libraries against disease targets, and the barcodes reveal the “hit molecules” with the strongest binding potential. It’s like searching for needles in a haystack, but with a DNA-powered map!
Excelra’s data analysis solutions unlock the true potential of DELs, accelerating your discovery process and opening doors to previously untreatable diseases.
Our algorithms and customized pipelines handle terabytes of data with ease, transforming it into actionable insights that guide your research towards the most promising candidates.
Analyse complex datasets at lightning speed, denoising the impact of false positives, pinpoint the molecules with the highest therapeutic potential and save valuable time and resources.
Our subject matter specialists will identify hidden patterns and trends from the avalanche of data, helping to optimize future DEL experiments and guide wiser research decisions.
Traditional analysis methods struggle with the sheer volume and complexity of DNA-encoded library technology.
Excelra’s solutions are built to handle this challenge:
We decontaminate and structure your data for meaningful analysis, ensuring clarity and accuracy.
Uncover hidden patterns and relationships within the data through interactive visualizations, making complex insights easily digestible.
Employ advanced algorithms to identify the most promising molecules and get biology-driven insights from our experts, guiding your research toward the most fruitful paths.
Case study
Our client is a European pharma company focused on discovering and developing small-molecule medicines with novel modes of action. A key stage of their research demands the processing of sequenced data through a next-generation sequencing (NGS) pipeline.
The client’s DNA-encoded library (DEL) had a large volume of data but low compound coverage. A pragmatic statistical approach using differential gene expression was required to reliably detect true positives and avoid the obstacles caused by the data.
We stand beside researchers, not just as service providers, but as collaborators in the quest for groundbreaking cures.
Focus resources on the most promising candidates, accelerating your path to clinical trials.
Gain data-driven insights from our domain experts to build even more effective DELs and experiments, maximizing your discovery potential.
Move promising drug candidates through the pipeline faster, bringing life-changing treatments to patients sooner.
Ready to embark on the DEL journey with Excelra? Contact us today and let’s unlock the secrets of these molecular treasure chests together. Turn data into discovery, and let’s rewrite the future of drug development.
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