Orogen Therapeutics Partners with Excelra for GOSTAR®

Partnership Strengthens Orogen Therapeutics’ AI-Driven Drug Discovery Platform

HYDERABAD, India / WOBURN, Mass (Dec 13, 2024): Excelra, a leading global data and digital insights organization, has announced a partnership with Orogen Therapeutics, an innovative DNA-Encoded Library (DEL) & Artificial Intelligence (AI)-driven biotechnology company, currently engaged in developing a portfolio of best-in-class small molecule treatments.

Integrating Excelra’s GOSTAR datasets enhances Orogen Therapeutics’ advanced drug discovery platform, which combines DEL with AI/ML and molecular simulations. This infusion of curated digital knowledge will expedite lead identification, optimization, and candidate selection. By unlocking the value within the GOSTAR data, the collaboration will be at the forefront of predicting chemical, biological, and physicochemical properties of novel compounds, accelerating the time- and resource-intensive stages of drug discovery. 

“Partnership with Excelra strengthens our position to deliver innovative clinical value to patients by leveraging curated prior art data in synergy with experimental science, AI, and new biology. We are very excited to add the Excelra’s GOSTAR to our arsenal of tools, as it is the industry gold standard in structured SAR intelligence. This addition will enhance our AI/ML platform to rapidly iterate and confidently simulate outcomes, thereby delivering effective therapies for patients with serious diseases,” said Dr. Artem Evdokimov, Head of Research at Orogen Therapeutics.

“Technologies such as AI/ML and quantum simulation are accelerating the development of therapies, and GOSTAR helps break a critical bottleneck in predictive modeling for drug discovery by providing high-quality, clean, and annotated datasets. As a result, biotechs and AI/ML companies are able to rapidly simulate and clearly identify patterns and extrapolate those findings into potential new areas of discovery,” said Norman Azoulay, Vice President, Platforms and Data, Excelra. 

 About Excelra’s GOSTAR®

 Excelra’s GOSTAR provides a unique 360⁰ view of over 10 million small molecules. The content in GOSTAR is meticulously curated using a proprietary QMS-ISO-certified process. It captures the most up-to-date view of the chemical space with information on chemical structures and their biological properties, including binding, in-vitro, in-vivo, ADME, Tox, and physicochemical properties. GOSTAR is available as an application for users to seek, find, and discover compounds. In addition, it is offered via APIs and as a downloadable dataset to power in-house libraries and machine learning models.

 For more information about GOSTAR, visit https://www.excelra.com/databases/gostar/

About Orogen Therapeutics

 Orogen is a biotechnology company that aims to drive best-in-class therapies in a wide range of disease areas by integrating DEL-based drug discovery with AI, machine learning, and molecular simulations.

For more information, please visit orogentx.com