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Use Case

GOSTAR® Academia

Catalyzing research with GOSTAR® extensive SAR database.

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Comprehensive SAR Access

GOSTAR® streamlines academic research by offering a single, expansive SAR database, eliminating the need to consult multiple sources. Access over 9.7 million chemical structures and a wealth of SAR data, enabling a seamless transition from data gathering to breakthrough discovery. This database, designed by and for medicinal chemists, provides unparalleled coverage of the medicinal chemical space, fostering a deeper understanding and enabling forward-thinking research planning.

GOSTAR® Database by the Numbers

9.7

Chemical structures

120

Abstracts & Conferences

33

SAR Data

78

Companies & Institutes

77

Biological Targets

4

Patents Screened

9.7

Chemical structures

33

SAR Data

120

Abstracts & Conferences

78

Companies & Institutes

77

Biological Targets

4

Patents Screened

Advanced Research Tools

With GOSTAR®, academic researchers gain access to precision tools designed for in-depth drug design analysis. From molecular pair analysis to efficiency plots, these tools offer advanced capabilities, including detailed compound-target affinity data and comprehensive profiles spanning pharmacokinetics, efficacy, metabolism, and toxicity. Such a suite of tools facilitates the design and testing of novel compounds, guiding researchers through complex datasets and enhancing their discovery process.

Data Visualization & Analysis

Empower your research with GOSTAR®’s data visualization capabilities, such as intuitive heatmaps that provide immediate insights into potential off-target activities of drug candidates. This visual approach simplifies complex data interpretation, allowing researchers to swiftly draw meaningful conclusions and advance towards new therapeutic discoveries. GOSTAR® presents data in a user-friendly format, expediting the transition from concept to peer-reviewed journal publications.

Data Visualization & Analysis

Empower your research with GOSTAR®’s data visualization capabilities, such as intuitive heatmaps that provide immediate insights into potential off-target activities of drug candidates. This visual approach simplifies complex data interpretation, allowing researchers to swiftly draw meaningful conclusions and advance towards new therapeutic discoveries. GOSTAR® presents data in a user-friendly format, expediting the transition from concept to peer-reviewed journal publications.

Advance Academic Publishing

GOSTAR® significantly aids academic researchers in authoring distinguished publications. It offers a database replete with 9.7 million chemical structures and 33 million SAR points, providing robust support for high-quality research papers. This wealth of data enables a thorough validation of hypotheses and enhances the substantiation of scientific arguments, essential for journal articles, reviews, and systematic studies. GOSTAR®’s reliable and expansive dataset not only underpins detailed research findings but also facilitates the contribution of substantial advancements to scientific literature.

Publications Citing GOSTAR®

GOSTAR® is a trusted ally in academic research, consistently featured in key studies that shape the future of drug discovery. Its extensive data drives scientific innovation, as evidenced in the curated selection of publications below

The Tools to Provide Clarity

GOSTAR® enables early discovery in drug development by providing normalized compound–target affinity data as well as comprehensive pharmacokinetic, efficacy, metabolic, and toxicity profiles. It enables medicinal chemists to build powerful searches which provide detailed insight into the entire pharmaceutical space. Find a wealth of data in GOSTAR®.

The drug-target interaction heatmap facilitates decision-making about the potential off-target activity of drug candidates early in drug development and drug repurposing workflows. GOSTAR® presents these findings in a visually intuitive manner, allowing end-users to easily interpret the data and draw conclusions. Go from data to understanding faster with GOSTAR®.

Matched molecular pair analysis is a powerful tool for determining which compound to design and test next. Computer algorithms analyse data in an unbiased manner to create design guidelines that will allow medicinal chemists to propose better compounds that reduce the number of design cycles. GOSTAR® provides tools for determining the matched molecular pairs and analysing activity landscapes across compound datasets. Design more effective compounds with GOSTAR®.

Lipophilicity is an important factor in determining the binding affinity of a drug to protein targets, as well as influencing ADMET properties. As a result, the combination of high target potency and high lipophilicity may increase the likelihood of ADMET-related attrition. Therefore, medicinal chemistry optimization needs to be balanced and multidimensional. GOSTAR® empowers medicinal chemists to efficiently explore the property space of compounds against a variety of bioactivity endpoints. Discover your next breakthrough with GOSTAR®.

What our customers say

Excelra responds quickly to provide the most recent patent and journal data to the GOSTAR® database.

Hanjo Kim
Deputy Head of Research, Standigm

Knowledge Hub

GOSTAR® Updates: The Latest Feature Enhancements

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GOSTAR®: the largest online medicinal chemistry intelligence database

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Analyzer in GOSTAR®: Matched Molecular Pair Analysis

GOSTAR® is an integrated platform of various standalone databases with cross-indexing of chemical compounds of…

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More use cases

Pharma & Biotech

GOSTAR® is pivotal for Pharma & Biotech, offering a SAR database that goes beyond chemistry to include activity, affinity, ADME, toxicology, physicochemical and other data relevant to drug design and discovery. The ontologies, format and interface are well designed to suit your needs.

AI / ML

Boost AI-driven drug discovery with GOSTAR®. It provides a highly normalized, QMS-ISO certified quality data set that can be used to train ML algorithms and help drive the search for novel compounds.

Expand your academic research horizons with GOSTAR®

Tell us about your study areas, and let’s push the boundaries of scientific knowledge together.

For evaluation & paid license requests:
gostardb@excelra.com

For product queries & support:
support.gostar@excelra.com

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