PK/PD Modeling for Dose Regulation

Optimizing Treatment Efficacy With Precision Dose Regulation

Our client’s requirement

Our client partnered with Excelra to enhance treatment efficacy by developing a PK/PD (Pharmacokinetic/Pharmacodynamic) model to accurately assess drug dosages. This involved intricate analysis of host enzyme kinetics and physiological factors to determine the most effective and precise drug dosing.

Our approach

We delineated critical host compartments, formulating equations for enzyme kinetics, and integrating physiological data into dosage calculations. Leveraging differential equations, we fine-tuned dose regulation to achieve optimal treatment efficacy over time.